Version 5.4
| Mus musculus Gene: Efemp2 | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-131786.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Efemp2 | ||||||||
| Gene Name | epidermal growth factor-containing fibulin-like extracellular matrix protein 2 | ||||||||
| Synonyms | 0610011K11Rik; Fbln4; MBP1 | ||||||||
| Species | Mus musculus | ||||||||
| Ensembl Gene | ENSMUSG00000024909 | ||||||||
| Encoded Proteins |
epidermal growth factor-containing fibulin-like extracellular matrix protein 2
epidermal growth factor-containing fibulin-like extracellular matrix protein 2
epidermal growth factor-containing fibulin-like extracellular matrix protein 2
epidermal growth factor-containing fibulin-like extracellular matrix protein 2
epidermal growth factor-containing fibulin-like extracellular matrix protein 2
epidermal growth factor-containing fibulin-like extracellular matrix protein 2
epidermal growth factor-containing fibulin-like extracellular matrix protein 2
epidermal growth factor-containing fibulin-like extracellular matrix protein 2
epidermal growth factor-containing fibulin-like extracellular matrix protein 2
epidermal growth factor-containing fibulin-like extracellular matrix protein 2
epidermal growth factor-containing fibulin-like extracellular matrix protein 2
epidermal growth factor-containing fibulin-like extracellular matrix protein 2
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| Protein Structure | |||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000172638:
A large number of extracellular matrix proteins have been found to contain variations of the epidermal growth factor (EGF) domain and have been implicated in functions as diverse as blood coagulation, activation of complement and determination of cell fate during development. The protein encoded by this gene contains four EGF2 domains and six calcium-binding EGF2 domains. This gene is necessary for elastic fiber formation and connective tissue development. Defects in this gene are cause of an autosomal recessive cutis laxa syndrome. Alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Jan 2011] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 19:5473973-5481853 | ||||||||
| Strand | Forward strand | ||||||||
| Band | A | ||||||||
| Transcripts | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 44 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||||
| NETPATH | |||||||||
| REACTOME |
Elastic fibre formation pathway
Molecules associated with elastic fibres pathway
Extracellular matrix organization pathway
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| KEGG | |||||||||
| INOH | |||||||||
| PID NCI | |||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||
| NETPATH | |||||||||
| REACTOME |
Molecules associated with elastic fibres pathway
Elastic fibre formation pathway
Extracellular matrix organization pathway
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| KEGG | |||||||||
| INOH | |||||||||
| PID NCI | |||||||||
| Cross-References | |||||||||
| SwissProt | |||||||||
| TrEMBL | E9PYW6 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 58859 | ||||||||
| UniGene | Mm.276367 Mm.402293 | ||||||||
| RefSeq | NM_001164352 NM_021474 XM_006531806 XM_006531808 XM_006531810 XM_006531811 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS29466 CCDS50358 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| MGI ID | MGI:1891209 | ||||||||
| MGI Symbol | Efemp2 | ||||||||
| EMBL | AC126029 | ||||||||
| GenPept | |||||||||
| RNA Seq Atlas | 58859 | ||||||||