Version 5.4
Mus musculus Gene: Fhod3
Summary
InnateDB Gene IDBG-131938.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Fhod3
Gene Name formin homology 2 domain containing 3
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000034295
Encoded Proteins
IDBP-131940
formin homology 2 domain containing 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000134775:
Proteins that contain formin (FMN1; MIM 136535) homology (FH) domains, such as FHOD3, play a role in regulation of the actin cytoskeleton (Kanaya et al., 2005 [PubMed 15966898]).[supplied by OMIM, Apr 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:24709445-25133500
Strand Forward strand
Band A2
Transcripts
ENSMUST00000037097 ENSMUSP00000041361
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0003779 actin binding
GO:0005488 binding
GO:0005515 protein binding
Biological Process
GO:0030837 negative regulation of actin filament polymerization
GO:0045214 sarcomere organization
GO:0051639 actin filament network formation
GO:0055003 cardiac myofibril assembly
Cellular Component
GO:0005730 nucleolus
GO:0005865 striated muscle thin filament
GO:0030017 sarcomere
GO:0030018 Z disc
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000134775
View Gene Order
ENSBTAG00000021581
Not yet available
Cross-References
SwissProt Q76LL6
TrEMBL Q6P9T5
UniProt Splice Variant
Entrez Gene 225288
UniGene Mm.329322
RefSeq NM_175276
OMIM
CCDS CCDS29104
HPRD
IMGT
MGI ID MGI:1925847
MGI Symbol Fhod3
EMBL AB078608 AB078609 AB100088 AK220413 BC060607 BC138046
GenPept AAH60607 AAI38047 BAC98302 BAC98303 BAC98348 BAD90459
RNA Seq Atlas 225288

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca