Version 5.4
Mus musculus Gene: Celf4
Summary
InnateDB Gene IDBG-132249.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Celf4
Gene Name CUGBP, Elav-like family member 4
Synonyms A230070D14Rik; Brul4; BRUNOL-4; Brunol4; C130060B05Rik
Species Mus musculus
Ensembl Gene ENSMUSG00000024268
Encoded Proteins
IDBP-132251
CUGBP, Elav-like family member 4
IDBP-248804
CUGBP, Elav-like family member 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000101489:
Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:25477632-25753983
Strand Reverse strand
Band A2
Transcripts
ENSMUST00000025117 ENSMUSP00000025117
ENSMUST00000115816 ENSMUSP00000111483
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003729 mRNA binding
GO:0042835 BRE binding
Biological Process
GO:0000380 alternative mRNA splicing, via spliceosome
GO:0000381 regulation of alternative mRNA splicing, via spliceosome
GO:0006376 mRNA splice site selection
GO:0048026 positive regulation of mRNA splicing, via spliceosome
GO:0090394 negative regulation of excitatory postsynaptic membrane potential
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000101489
View Gene Order
ENSBTAG00000004940
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.266435 Mm.399968 Mm.399990 Mm.416638
RefSeq NM_001146292 NM_001146293 NM_001146294 NM_001174074 NM_133195 XM_006525511 XM_006525512 XM_006525514 XM_006525520
OMIM
CCDS CCDS29106 CCDS50241
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca