Version 5.4
Homo sapiens Gene: PPP6R2
Summary
InnateDB Gene IDBG-13286.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PPP6R2
Gene Name protein phosphatase 6, regulatory subunit 2
Synonyms KIAA0685; PP6R2; SAP190; SAPS2
Species Homo sapiens
Ensembl Gene ENSG00000100239
Encoded Proteins
IDBP-13288
protein phosphatase 6, regulatory subunit 2
IDBP-13290
protein phosphatase 6, regulatory subunit 2
IDBP-238908
protein phosphatase 6, regulatory subunit 2
IDBP-238910
protein phosphatase 6, regulatory subunit 2
IDBP-295555
protein phosphatase 6, regulatory subunit 2
IDBP-381154
protein phosphatase 6, regulatory subunit 2
IDBP-810201
protein phosphatase 6, regulatory subunit 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Protein phosphatase regulatory subunits, such as SAPS2, modulate the activity of protein phosphatase catalytic subunits by restricting substrate specificity, recruiting substrates, and determining the intracellular localization of the holoenzyme. SAPS2 is a regulatory subunit for the protein phosphatase-6 catalytic subunit (PPP6C; MIM 612725) (Stefansson and Brautigan, 2006 [PubMed 16769727]).[supplied by OMIM, Nov 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 22:50343304-50445090
Strand Forward strand
Band q13.33
Transcripts
ENST00000359139 ENSP00000352051
ENST00000216061 ENSP00000216061
ENST00000395744 ENSP00000379093
ENST00000395741 ENSP00000379090
ENST00000401672 ENSP00000384532
ENST00000427222 ENSP00000391595
ENST00000473283
ENST00000470046
ENST00000612753 ENSP00000478417
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 48 experimentally validated interaction(s) in this database.
Experimentally validated
Total 48 [view]
Protein-Protein 48 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005488 binding
GO:0005515 protein binding
Biological Process
Cellular Component
GO:0005737 cytoplasm
GO:0043231 intracellular membrane-bounded organelle
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000036561
View Gene Order
ENSBTAG00000018660
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.729287
RefSeq NM_001242898 NM_001242899 NM_001242900 NM_014678 XM_005261960 XM_006724430 XM_006724433 XM_006724434 XM_006724435
HUGO
OMIM
CCDS CCDS33681 CCDS56235 CCDS56236 CCDS74881
HPRD 11102
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca