Version 5.4
Mus musculus Gene: Scyl1
Summary
InnateDB Gene IDBG-133326.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Scyl1
Gene Name SCY1-like 1 (S. cerevisiae)
Synonyms 2810011O19Rik; C85140; mdf; mfd; Ntkl; p105
Species Mus musculus
Ensembl Gene ENSMUSG00000024941
Encoded Proteins
IDBP-133328
SCY1-like 1 (S. cerevisiae)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000142186:
This gene encodes a transcriptional regulator belonging to the SCY1-like family of kinase-like proteins. The protein has a divergent N-terminal kinase domain that is thought to be catalytically inactive, and can bind specific DNA sequences through its C-terminal domain. It activates transcription of the telomerase reverse transcriptase and DNA polymerase beta genes. The protein has been localized to the nucleus, and also to the cytoplasm and centrosomes during mitosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:5758427-5771401
Strand Reverse strand
Band A
Transcripts
ENSMUST00000025890 ENSMUSP00000025890
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004672 protein kinase activity
GO:0005488 binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
Biological Process
GO:0006468 protein phosphorylation
GO:0006890 retrograde vesicle-mediated transport, Golgi to ER
Cellular Component
GO:0005737 cytoplasm
GO:0005793 endoplasmic reticulum-Golgi intermediate compartment
GO:0005794 Golgi apparatus
GO:0005801 cis-Golgi network
GO:0005815 microtubule organizing center
GO:0016020 membrane
GO:0030126 COPI vesicle coat
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000142186
View Gene Order
ENSBTAG00000006740
Not yet available
Cross-References
SwissProt Q9EQC5
TrEMBL B0LAE0 R4H4Y7
UniProt Splice Variant
Entrez Gene 78891
UniGene
RefSeq NM_023912 XM_006531856
OMIM
CCDS CCDS29480
HPRD
IMGT
MGI ID MGI:1931787
MGI Symbol Scyl1
EMBL AF276514 AK134356 AK144134 AK145869 AK161813 BC034519 EF437375 HM856325
GenPept AAG17393 AAH34519 ABS83534 ADT64112 BAE22111 BAE25720 BAE26711 BAE36588
RNA Seq Atlas 78891

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca