Version 5.4
Mus musculus Gene: Maml2
Summary
InnateDB Gene IDBG-134014.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Maml2
Gene Name mastermind like 2 (Drosophila)
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000031925
Encoded Proteins
IDBP-134016
mastermind like 2 (Drosophila)
IDBP-539692
mastermind like 2 (Drosophila)
IDBP-741882
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000184384:
Gene Information
Type Protein coding
Genomic Location Chromosome 9:13619990-13709533
Strand Forward strand
Band A1
Transcripts
ENSMUST00000034401 ENSMUSP00000034401
ENSMUST00000159294 ENSMUSP00000124083
ENSMUST00000161245
ENSMUST00000177755 ENSMUSP00000136866
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003713 transcription coactivator activity
Biological Process
GO:0007219 Notch signaling pathway
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
Cellular Component
GO:0005634 nucleus
GO:0005794 Golgi apparatus
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000184384
View Gene Order
ENSBTAG00000037962
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu04330
Notch signaling pathway pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_3
Notch pathway
REACTOME
REACT_118780
NOTCH1 Intracellular Domain Regulates Transcription pathway
REACT_118568
Pre-NOTCH Transcription and Translation pathway
REACT_160243
Constitutive Signaling by NOTCH1 PEST Domain Mutants pathway
REACT_160254
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants pathway
REACT_14835
Notch-HLH transcription pathway pathway
REACT_12627
Generic Transcription Pathway pathway
REACT_160082
Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant pathway
REACT_118744
Pre-NOTCH Expression and Processing pathway
REACT_160214
Signaling by NOTCH1 in Cancer pathway
REACT_160099
FBXW7 Mutants and NOTCH1 in Cancer pathway
REACT_111102
Signal Transduction pathway
REACT_118721
Signaling by NOTCH2 pathway
REACT_160301
Signaling by NOTCH1 PEST Domain Mutants in Cancer pathway
REACT_160248
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer pathway
REACT_299
Signaling by NOTCH pathway
REACT_118859
Signaling by NOTCH1 pathway
REACT_160133
Signaling by NOTCH1 HD Domain Mutants in Cancer pathway
REACT_163910
NOTCH2 intracellular domain regulates transcription pathway
REACT_71
Gene Expression pathway
REACT_116125
Disease pathway
KEGG
hsa04330
Notch signaling pathway pathway
INOH
INOH website
Notch signaling pathway pathway
INOH website
TGF-beta signaling pathway
INOH website
BMP2 signaling pathway
PID NCI
Cross-References
SwissProt
TrEMBL E9Q7L5
UniProt Splice Variant
Entrez Gene 270118
UniGene Mm.116898 Mm.393962
RefSeq NM_173776 NM_001013813
OMIM
CCDS CCDS52723
HPRD
IMGT
MGI ID MGI:2389460
MGI Symbol Maml2
EMBL AC155923 AC169127
GenPept
RNA Seq Atlas 270118

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca