Version 5.4
Mus musculus Gene: Stx11
Summary
InnateDB Gene IDBG-134028.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Stx11
Gene Name syntaxin 11
Synonyms 5830405C08Rik
Species Mus musculus
Ensembl Gene ENSMUSG00000039232
Encoded Proteins
IDBP-134030
syntaxin 11
IDBP-627916
syntaxin 11
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000135604:
This gene encodes a member of the syntaxin family. Syntaxins have been implicated in the targeting and fusion of intracellular transport vesicles. This family member may regulate protein transport among late endosomes and the trans-Golgi network. Mutations in this gene have been associated with familial hemophagocytic lymphohistiocytosis. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:12939983-12964259
Strand Reverse strand
Band A2
Transcripts
ENSMUST00000042861 ENSMUSP00000046243
ENSMUST00000163425 ENSMUSP00000132758
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 15 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 15 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005484 SNAP receptor activity
GO:0005515 protein binding
Biological Process
GO:0001913 T cell mediated cytotoxicity
GO:0006886 intracellular protein transport
GO:0016192 vesicle-mediated transport
GO:0042267 natural killer cell mediated cytotoxicity
GO:0043312 neutrophil degranulation
GO:0043316 cytotoxic T cell degranulation
GO:0043320 natural killer cell degranulation
Cellular Component
GO:0005794 Golgi apparatus
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000135604
View Gene Order
ENSBTAG00000011236
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu04130
SNARE interactions in vesicular transport pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa04130
SNARE interactions in vesicular transport pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.248648 Mm.416283
RefSeq NM_001163590 NM_001163591 NM_029075 XM_006512888
OMIM
CCDS CCDS48500
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca