Mus musculus Gene: Mrps16
Summary
InnateDB Gene IDBG-134803.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mrps16
Gene Name mitochondrial ribosomal protein S16
Synonyms 1500011E11Rik; Mprs16
Species Mus musculus
Ensembl Gene ENSMUSG00000049960
Encoded Proteins
mitochondrial ribosomal protein S16
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000182180:
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S16P family. The encoded protein is one of the most highly conserved ribosomal proteins between mammalian and yeast mitochondria. Three pseudogenes (located at 8q21.3, 20q13.32, 22q12-q13.1) for this gene have been described. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:20391231-20393555
Strand Reverse strand
Band A3
Transcripts
ENSMUST00000061444 ENSMUSP00000055619
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 27 interaction(s) predicted by orthology.
Predicted by orthology
Total 27 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
Biological Process
GO:0006412 translation
GO:0008150 biological_process
Cellular Component
GO:0005622 intracellular
GO:0005739 mitochondrion
GO:0005763 mitochondrial small ribosomal subunit
GO:0005840 ribosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Mitochondrial translation pathway
Organelle biogenesis and maintenance pathway
Mitochondrial translation elongation pathway
Mitochondrial translation initiation pathway
Mitochondrial translation termination pathway
KEGG
Ribosome pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Organelle biogenesis and maintenance pathway
Mitochondrial translation pathway
Mitochondrial translation initiation pathway
Mitochondrial translation termination pathway
Mitochondrial translation elongation pathway
Mitochondrial translation initiation pathway
Mitochondrial translation elongation pathway
Mitochondrial translation pathway
Mitochondrial translation termination pathway
Organelle biogenesis and maintenance pathway
KEGG
Ribosome pathway
INOH
PID NCI
Cross-References
SwissProt Q9CPX7
TrEMBL
UniProt Splice Variant
Entrez Gene 66242
UniGene Mm.389481
RefSeq NM_025440
OMIM
CCDS CCDS36817
HPRD
IMGT
MGI ID MGI:1913492
MGI Symbol Mrps16
EMBL AB049949 AK005206 AK019243 BC024656
GenPept AAH24656 BAB23884 BAB31623 BAB41002
RNA Seq Atlas 66242