Version 5.4
Mus musculus Gene: Nmbr
Summary
InnateDB Gene IDBG-134814.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Nmbr
Gene Name neuromedin B receptor
Synonyms BB182387
Species Mus musculus
Ensembl Gene ENSMUSG00000019865
Encoded Proteins
IDBP-134816
neuromedin B receptor
IDBP-788131
neuromedin B receptor
IDBP-788134
neuromedin B receptor
IDBP-788138
neuromedin B receptor
IDBP-788139
neuromedin B receptor
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000135577:
Neuromedin B receptor binds neuromedin B, a potent mitogen and growth factor for normal and neoplastic lung and for gastrointestinal epithelial tissue. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:14705591-14770850
Strand Forward strand
Band A2
Transcripts
ENSMUST00000020015 ENSMUSP00000020015
ENSMUST00000191238 ENSMUSP00000139695
ENSMUST00000187449
ENSMUST00000188021
ENSMUST00000190114 ENSMUSP00000140754
ENSMUST00000186175
ENSMUST00000186382 ENSMUSP00000139612
ENSMUST00000190751 ENSMUSP00000140223
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004930 G-protein coupled receptor activity
GO:0004946 bombesin receptor activity
Biological Process
GO:0007186 G-protein coupled receptor signaling pathway
GO:0031989 bombesin receptor signaling pathway
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000135577
View Gene Order
ENSBTAG00000043954
Not yet available
Pathways
NETPATH
REACTOME
REACT_223625
GPCR downstream signaling pathway
REACT_254215
Signaling by GPCR pathway
REACT_261161
Class A/1 (Rhodopsin-like receptors) pathway
REACT_188573
Gastrin-CREB signalling pathway via PKC and MAPK pathway
REACT_231468
GPCR ligand binding pathway
REACT_235286
Peptide ligand-binding receptors pathway
REACT_207651
G alpha (q) signalling events pathway
REACT_188257
Signal Transduction pathway
KEGG
mmu04080
Neuroactive ligand-receptor interaction pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_18283
G alpha (q) signalling events pathway
REACT_120966
Gastrin-CREB signalling pathway via PKC and MAPK pathway
REACT_14819
Peptide ligand-binding receptors pathway
REACT_14828
Class A/1 (Rhodopsin-like receptors) pathway
REACT_14797
Signaling by GPCR pathway
REACT_111102
Signal Transduction pathway
REACT_19184
GPCR downstream signaling pathway
REACT_21340
GPCR ligand binding pathway
KEGG
hsa04080
Neuroactive ligand-receptor interaction pathway
INOH
PID NCI
Cross-References
SwissProt O54799
TrEMBL Q0VEH1
UniProt Splice Variant
Entrez Gene 18101
UniGene
RefSeq NM_008703
OMIM
CCDS CCDS23707
HPRD
IMGT
MGI ID MGI:1100525
MGI Symbol Nmbr
EMBL AB010281 BC119237 CH466562
GenPept AAI19238 BAA24405 EDL03484
RNA Seq Atlas 18101

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca