InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Atp5c1

Summary

InnateDB Gene

IDBG-135543.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Atp5c1

Gene Name

ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1

Synonyms

1700094F02Rik

Species

Mus musculus

Ensembl Gene

ENSMUSG00000025781

Encoded Proteins

IDBP-135545

ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1

IDBP-250793

ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1

IDBP-250795

ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1

IDBP-532262

ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1

IDBP-532120

ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1

IDBP-533977

ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1

IDBP-538116

ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000165629:
This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel consists of three main subunits (a, b, c). This gene encodes the gamma subunit of the catalytic core. Alternatively spliced transcript variants encoding different isoforms have been identified. This gene also has a pseudogene on chromosome 14. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 2:10056016-10080510

Strand

Reverse strand

Band

Transcripts

ENSMUST00000026887	ENSMUSP00000026887
ENSMUST00000114897	ENSMUSP00000110547
ENSMUST00000114896	ENSMUSP00000110546
ENSMUST00000145530	ENSMUSP00000116508
ENSMUST00000153554	ENSMUSP00000116368
ENSMUST00000139810	ENSMUSP00000123100
ENSMUST00000130067	ENSMUSP00000117182

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 40 interaction(s) predicted by orthology.

Experimentally validated
Total	6 [view]
Protein-Protein	6 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	40 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0016887	ATPase activity
GO:0044822	poly(A) RNA binding
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism
GO:0046961	proton-transporting ATPase activity, rotational mechanism

Biological Process

GO:0006200	ATP catabolic process
GO:0015986	ATP synthesis coupled proton transport

Cellular Component

GO:0005739	mitochondrion
GO:0005743	mitochondrial inner membrane
GO:0005753	mitochondrial proton-transporting ATP synthase complex
GO:0016020	membrane
GO:0045261	proton-transporting ATP synthase complex, catalytic core F(1)
GO:0070062	extracellular vesicular exosome