Version 5.4
| Mus musculus Gene: Oscar | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-135635.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Oscar | ||||||||
| Gene Name | osteoclast associated receptor | ||||||||
| Synonyms | |||||||||
| Species | Mus musculus | ||||||||
| Ensembl Gene | ENSMUSG00000054594 | ||||||||
| Encoded Proteins |
osteoclast associated receptor
osteoclast associated receptor
osteoclast associated receptor
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000170909:
Osteoclasts are multinucleated cells that resorb bone and are essential for bone homeostasis. This gene encodes an osteoclast-associated receptor (OSCAR), which is a member of the leukocyte receptor complex (LRC) protein family that plays critical roles in the regulation of both innate and adaptive immune responses. Different from the other LRC members, OSCAR expression is detected specifically in preosteoclasts or mature osteoclasts. OSCAR may be an important bone-specific regulator of osteoclast differentiation. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 7:3609813-3616157 | ||||||||
| Strand | Reverse strand | ||||||||
| Band | A1 | ||||||||
| Transcripts |
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| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||||
| NETPATH | |||||||||
| REACTOME | |||||||||
| KEGG |
Osteoclast differentiation pathway
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| INOH | |||||||||
| PID NCI | |||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||
| NETPATH |
RANKL pathway
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| REACTOME | |||||||||
| KEGG |
Osteoclast differentiation pathway
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| INOH | |||||||||
| PID NCI | |||||||||
| Cross-References | |||||||||
| SwissProt | Q8VBT3 | ||||||||
| TrEMBL | D3YXX9 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 232790 | ||||||||
| UniGene | Mm.358882 | ||||||||
| RefSeq | NM_001290377 NM_175632 XM_006539749 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS20718 CCDS71872 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| MGI ID | MGI:2179720 | ||||||||
| MGI Symbol | Oscar | ||||||||
| EMBL | AC171680 AF391159 AF391160 AF391161 | ||||||||
| GenPept | AAL68492 AAL68493 AAL68494 | ||||||||
| RNA Seq Atlas | 232790 | ||||||||