Mus musculus Gene: Kcnmb2
Summary
InnateDB Gene IDBG-136457.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Kcnmb2
Gene Name potassium large conductance calcium-activated channel, subfamily M, beta member 2
Synonyms 2700049B16Rik; 3110031N04Rik
Species Mus musculus
Ensembl Gene ENSMUSG00000037610
Encoded Proteins
potassium large conductance calcium-activated channel, subfamily M, beta member 2
potassium large conductance calcium-activated channel, subfamily M, beta member 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000197584:
MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which decreases the activation time of MaxiK alpha subunit currents. Two variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:31902507-32200180
Strand Forward strand
Band A3
Transcripts
ENSMUST00000119310 ENSMUSP00000112531
ENSMUST00000119970 ENSMUSP00000113234
ENSMUST00000178668 ENSMUSP00000136596
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0015269 calcium-activated potassium channel activity
Biological Process
GO:0005513 detection of calcium ion
GO:0006813 potassium ion transport
GO:0019228 neuronal action potential
GO:0071805 potassium ion transmembrane transport
Cellular Component
GO:0008076 voltage-gated potassium channel complex
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Platelet homeostasis pathway
Hemostasis pathway
Potassium Channels pathway
Ca2+ activated K+ channels pathway
cGMP effects pathway
Nitric oxide stimulates guanylate cyclase pathway
Neuronal System pathway
KEGG
Vascular smooth muscle contraction pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
cGMP effects pathway
Nitric oxide stimulates guanylate cyclase pathway
Platelet homeostasis pathway
Ca2+ activated K+ channels pathway
Neuronal System pathway
Potassium Channels pathway
Hemostasis pathway
KEGG
Vascular smooth muscle contraction pathway
INOH
PID NCI
Cross-References
SwissProt Q9CZM9
TrEMBL
UniProt Splice Variant
Entrez Gene 72413
UniGene Mm.64790
RefSeq NM_028231 XM_006535550 XM_006535549
OMIM
CCDS CCDS17292
HPRD
IMGT
MGI ID MGI:1919663
MGI Symbol Kcnmb2
EMBL AK012400 AY062429 BC046227 BC058957
GenPept AAH46227 AAH58957 AAL38982 BAB28216
RNA Seq Atlas 72413