Version 5.4
Homo sapiens Gene: POMT2
Summary
InnateDB Gene IDBG-13659.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol POMT2
Gene Name protein-O-mannosyltransferase 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000009830
Encoded Proteins
IDBP-13661
protein-O-mannosyltransferase 2
IDBP-599627
protein-O-mannosyltransferase 2
IDBP-585129
protein-O-mannosyltransferase 2
IDBP-599551
protein-O-mannosyltransferase 2
IDBP-593948
protein-O-mannosyltransferase 2
IDBP-601193
protein-O-mannosyltransferase 2
IDBP-597387
protein-O-mannosyltransferase 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is an O-mannosyltransferase that requires interaction with the product of the POMT1 gene for enzymatic function. The encoded protein is found in the membrane of the endoplasmic reticulum. Defects in this gene are a cause of Walker-Warburg syndrome (WWS).[provided by RefSeq, Oct 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:77274956-77320884
Strand Reverse strand
Band q24.3
Transcripts
ENST00000261534 ENSP00000261534
ENST00000452340
ENST00000554767
ENST00000556394 ENSP00000451967
ENST00000555710 ENSP00000451730
ENST00000556446
ENST00000556171 ENSP00000451651
ENST00000555134
ENST00000554564
ENST00000554884
ENST00000553880
ENST00000557675
ENST00000556404
ENST00000556851
ENST00000557289 ENSP00000451115
ENST00000553863
ENST00000556326 ENSP00000450630
ENST00000555675
ENST00000554948 ENSP00000452060
ENST00000556880
ENST00000555788
ENST00000557525
ENST00000602717
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 0
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000030 mannosyltransferase activity
GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity
GO:0046872 metal ion binding
Biological Process
GO:0006493 protein O-linked glycosylation
GO:0035269 protein O-linked mannosylation
GO:0097502 mannosylation
Cellular Component
GO:0005789 endoplasmic reticulum membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000034126
View Gene Order
ENSBTAG00000002704
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa00514
Other types of O-glycan biosynthesis pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.132989
RefSeq NM_013382
HUGO
OMIM
CCDS CCDS9857
HPRD 09592
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca