Mus musculus Gene: Hist1h2bc
Summary
InnateDB Gene IDBG-136618.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Hist1h2bc
Gene Name histone cluster 1, H2bc
Synonyms 2610022J01Rik; H2bfs; R74621
Species Mus musculus
Ensembl Gene ENSMUSG00000018102
Encoded Proteins
histone cluster 1, H2bc
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a member of the histone H2B family and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. [provided by RefSeq, Mar 2014]
Gene Information
Type Protein coding
Genomic Location Chromosome 13:23684199-23692488
Strand Forward strand
Band A3.1
Transcripts
ENSMUST00000018246 ENSMUSP00000018246
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0043565 sequence-specific DNA binding
GO:0046982 protein heterodimerization activity
Biological Process
GO:0006334 nucleosome assembly
Cellular Component
GO:0000786 nucleosome
GO:0005622 intracellular
GO:0005634 nucleus
GO:0005654 nucleoplasm
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
Meiotic Recombination pathway
Meiotic Synapsis pathway
Mus musculus biological processes pathway
NoRC negatively regulates rRNA expression pathway
Chromatin organization pathway
HATs acetylate histones pathway
Meiotic synapsis pathway
Cell Cycle pathway
NoRC negatively regulates rRNA expression pathway
Chromatin modifying enzymes pathway
Epigenetic regulation of gene expression pathway
Gene Expression pathway
DNA methylation pathway
Negative epigenetic regulation of rRNA expression pathway
Meiosis pathway
KEGG
Systemic lupus erythematosus pathway
INOH
PID NCI
Cross-References
SwissProt Q6ZWY9
TrEMBL
UniProt Splice Variant
Entrez Gene 68024
UniGene Mm.261676
RefSeq NM_001290380 NM_023422
OMIM
CCDS CCDS26357
HPRD
IMGT
MGI ID MGI:1915274
MGI Symbol Hist1h2bc
EMBL AK005407 AK011516 AK030546 AK049948 AL592149 AY158934 AY158936 AY158937 BC019673 BC060304 BC069889
GenPept AAH19673 AAH60304 AAH69889 AAO06244 AAO06246 AAO06247 BAB24007 BAB27670 BAC27014 BAC34000 CAI24894
RNA Seq Atlas 319179 319181 68024