Version 5.4
Mus musculus Gene: Olfr18
Summary
InnateDB Gene IDBG-136996.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Olfr18
Gene Name olfactory receptor 18
Synonyms MOR145-1; MTPCR34
Species Mus musculus
Ensembl Gene ENSMUSG00000066896
Encoded Proteins
IDBP-136998
olfactory receptor 18
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:20313892-20336094
Strand Reverse strand
Band A3
Transcripts
ENSMUST00000086473 ENSMUSP00000083664
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004930 G-protein coupled receptor activity
GO:0004984 olfactory receptor activity
Biological Process
GO:0007186 G-protein coupled receptor signaling pathway
GO:0007608 sensory perception of smell
GO:0050911 detection of chemical stimulus involved in sensory perception of smell
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
REACT_223625
GPCR downstream signaling pathway
REACT_254215
Signaling by GPCR pathway
REACT_252270
Olfactory Signaling Pathway pathway
REACT_188257
Signal Transduction pathway
KEGG
mmu04740
Olfactory transduction pathway
INOH
PID NCI
Cross-References
SwissProt Q0VAX9
TrEMBL
UniProt Splice Variant
Entrez Gene 18315
UniGene Mm.246524
RefSeq NM_146563
OMIM
CCDS CCDS40542
HPRD
IMGT
MGI ID MGI:109317
MGI Symbol Olfr18
EMBL AY073534 AY318053 BC120866 BC120868 X89686
GenPept AAI20867 AAI20869 AAL61197 AAP71350 CAA61833
RNA Seq Atlas 18315

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca