Version 5.4
| Mus musculus Gene: Dusp13 | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-137362.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Dusp13 | ||||||||
| Gene Name | dual specificity phosphatase 13 | ||||||||
| Synonyms | DUSP13A; DUSP13B; Gm1203; LMW-DSP6; MDSP; TMDP; TS-DSP6 | ||||||||
| Species | Mus musculus | ||||||||
| Ensembl Gene | ENSMUSG00000021768 | ||||||||
| Encoded Proteins |
dual specificity phosphatase 13
dual specificity phosphatase 13
dual specificity phosphatase 13
dual specificity phosphatase 13
dual specificity phosphatase 13
dual specificity phosphatase 13
dual specificity phosphatase 13
dual specificity phosphatase 13
dual specificity phosphatase 13
dual specificity phosphatase 13
dual specificity phosphatase 13
dual specificity phosphatase 13
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| Protein Structure | |||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
Members of the protein-tyrosine phosphatase superfamily cooperate with protein kinases to regulate cell proliferation and differentiation. This superfamily is separated into two families based on the substrate that is dephosphorylated. One family, the dual specificity phosphatases (DSPs) acts on both phosphotyrosine and phosphoserine/threonine residues. This gene encodes different but related DSP proteins through the use of non-overlapping open reading frames, alternate splicing, and presumed different transcription promoters. Expression of the distinct proteins from this gene has been found to be tissue specific and the proteins may be involved in postnatal development of specific tissues. A protein encoded by the upstream ORF was found in skeletal muscle, whereas the encoded protein from the downstream ORF was found only in testis. In humans, a similar pattern of expression was found. Multiple alternatively spliced transcript variants were described, but the full-length sequence of only some were determined. [provided by RefSeq, Jul 2008] Members of the protein-tyrosine phosphatase superfamily cooperate with protein kinases to regulate cell proliferation and differentiation. This superfamily is separated into two families based on the substrate that is dephosphorylated. One family, the dual specificity phosphatases (DSPs) acts on both phosphotyrosine and phosphoserine/threonine residues. This gene encodes different but related DSP proteins through the use of non-overlapping open reading frames, alternate splicing, and presumed different transcription promoters. Expression of the distinct proteins from this gene has been found to be tissue specific and the proteins may be involved in postnatal development of specific tissues. A protein encoded by the upstream ORF was found in skeletal muscle, whereas the encoded protein from the downstream ORF was found only in testis. In humans, a similar pattern of expression was found. Multiple alternatively spliced transcript variants were described, but the full-length sequence of only some were determined. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 14:21733394-21751181 | ||||||||
| Strand | Reverse strand | ||||||||
| Band | A3 | ||||||||
| Transcripts | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
| No orthologs found for this gene | |||||||||
| Cross-References | |||||||||
| SwissProt | |||||||||
| TrEMBL | D6RHL3 V9GXC2 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 27389 | ||||||||
| UniGene | Mm.390674 | ||||||||
| RefSeq | NM_001007268 NM_013849 XM_006519075 XM_006519076 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS26864 CCDS36821 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| MGI ID | MGI:1351599 | ||||||||
| MGI Symbol | Dusp13 | ||||||||
| EMBL | AC151533 | ||||||||
| GenPept | |||||||||
| RNA Seq Atlas | 27389 | ||||||||