InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Rsu1

Summary

InnateDB Gene

IDBG-137429.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Rsu1

Gene Name

Ras suppressor protein 1

Synonyms

rsp-1; RsuI

Species

Mus musculus

Ensembl Gene

ENSMUSG00000026727

Encoded Proteins

IDBP-137431

Ras suppressor protein 1

IDBP-251047

Ras suppressor protein 1

IDBP-532240

Ras suppressor protein 1

IDBP-537298

Ras suppressor protein 1

IDBP-541652

Ras suppressor protein 1

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000148484:
This gene encodes a protein that is involved in the Ras signal transduction pathway, growth inhibition, and nerve-growth factor induced differentiation processes, as determined in mouse and human cell line studies. In mouse, the encoded protein was initially isolated based on its ability to inhibit v-Ras transformation. Multiple alternatively spliced transcript variants for this gene have been reported; one of these variants was found only in glioma tumors. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 2:13076967-13271431

Strand

Reverse strand

Band

Transcripts

ENSMUST00000028059	ENSMUSP00000028059
ENSMUST00000114791	ENSMUSP00000110439
ENSMUST00000161912	ENSMUSP00000125279
ENSMUST00000162223
ENSMUST00000134551	ENSMUSP00000125338
ENSMUST00000131226
ENSMUST00000137670	ENSMUSP00000117460
ENSMUST00000129257

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	11 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0005515	protein binding

Biological Process

GO:0007265	Ras protein signal transduction
GO:2000179	positive regulation of neural precursor cell proliferation

Cellular Component

GO:0070062

extracellular vesicular exosome

Orthologs

Species

Homo sapiens

Bos taurus

Gene ID

Gene Order

ENSG00000148484

View Gene Order

ENSBTAG00000027446

Not yet available

Pathway Predictions based on Human Orthology Data

NETPATH

REACTOME

REACT_20580

Regulation of cytoskeletal remodeling and cell spreading by IPP complex components pathway

REACT_20649

Cell-extracellular matrix interactions pathway

REACT_111155

Cell-Cell communication pathway

REACT_20676

Cell junction organization pathway

REACT_214421

Regulation of cytoskeletal remodeling and cell spreading by IPP complex components pathway

REACT_214866

Cell junction organization pathway

REACT_206475

Cell-Cell communication pathway

REACT_213279

Cell-extracellular matrix interactions pathway

KEGG

INOH

PID NCI

Cross-References

SwissProt

TrEMBL

UniProt Splice Variant

Entrez Gene

UniGene

Mm.417336 Mm.905

RefSeq

NM_009105 XM_006497404 XM_006497405

OMIM

CCDS

CCDS15693

HPRD

IMGT

MGI ID

MGI Symbol

EMBL

GenPept

RNA Seq Atlas