Version 5.4
Mus musculus Gene: Npas3
Summary
InnateDB Gene IDBG-139307.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Npas3
Gene Name neuronal PAS domain protein 3
Synonyms 4930423H22Rik; bHLHe12
Species Mus musculus
Ensembl Gene ENSMUSG00000021010
Encoded Proteins
IDBP-139424
neuronal PAS domain protein 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000151322:
This gene encodes a member of the basic helix-loop-helix and PAS domain-containing family of transcription factors. The encoded protein is localized to the nucleus and may regulate genes involved in neurogenesis. Chromosomal abnormalities that affect the coding potential of this gene are associated with schizophrenia and mental retardation. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:53248677-54072175
Strand Forward strand
Band C1
Transcripts
ENSMUST00000101432 ENSMUSP00000098975
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0004871 signal transducer activity
GO:0005515 protein binding
GO:0046983 protein dimerization activity
Biological Process
GO:0001964 startle response
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0007165 signal transduction
GO:0007626 locomotory behavior
GO:0042711 maternal behavior
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000151322
View Gene Order
ENSBTAG00000004462
Not yet available
Cross-References
SwissProt
TrEMBL F8VQB2
UniProt Splice Variant
Entrez Gene 27386
UniGene Mm.247044 Mm.466545
RefSeq NM_013780 XM_006515938 XM_006515939 XM_006515940 XM_006515941 XM_006515942 XM_006515943
OMIM
CCDS CCDS25907
HPRD
IMGT
MGI ID MGI:1351610
MGI Symbol Npas3
EMBL AC120181 AC125451 AC139934 AC159634 CR974571 CT030137
GenPept
RNA Seq Atlas 27386

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca