Mus musculus Gene: P2rx6 | |||||||||||||||||
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Summary | |||||||||||||||||
InnateDB Gene | IDBG-139432.6 | ||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||
Gene Symbol | P2rx6 | ||||||||||||||||
Gene Name | purinergic receptor P2X, ligand-gated ion channel, 6 | ||||||||||||||||
Synonyms | P2rxl1; P2x6; P2xm | ||||||||||||||||
Species | Mus musculus | ||||||||||||||||
Ensembl Gene | ENSMUSG00000022758 | ||||||||||||||||
Encoded Proteins |
purinergic receptor P2X, ligand-gated ion channel, 6
purinergic receptor P2X, ligand-gated ion channel, 6
purinergic receptor P2X, ligand-gated ion channel, 6
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Protein Structure | |||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||
Entrez Gene | |||||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000099957:
The protein encoded by this gene belongs to the family of P2X receptors, which are ATP-gated ion channels and mediate rapid and selective permeability to cations. This gene is predominantly expressed in skeletal muscle, and regulated by p53. The encoded protein is associated with VE-cadherin at the adherens junctions of human umbilical vein endothelial cells. Alternative splicing results in multiple transcript variants. A related pseudogene, which is also located on chromosome 22, has been identified. [provided by RefSeq, Apr 2009] |
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Gene Information | |||||||||||||||||
Type | Protein coding | ||||||||||||||||
Genomic Location | Chromosome 16:17561885-17577800 | ||||||||||||||||
Strand | Forward strand | ||||||||||||||||
Band | A3 | ||||||||||||||||
Transcripts |
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Interactions | |||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||
Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||||||||||||
NETPATH | |||||||||||||||||
REACTOME | |||||||||||||||||
KEGG |
Calcium signaling pathway pathway
Neuroactive ligand-receptor interaction pathway
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INOH | |||||||||||||||||
PID NCI | |||||||||||||||||
Pathway Predictions based on Human Orthology Data | |||||||||||||||||
NETPATH | |||||||||||||||||
REACTOME | |||||||||||||||||
KEGG |
Neuroactive ligand-receptor interaction pathway
Calcium signaling pathway pathway
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INOH | |||||||||||||||||
PID NCI | |||||||||||||||||
Cross-References | |||||||||||||||||
SwissProt | |||||||||||||||||
TrEMBL | E9Q857 | ||||||||||||||||
UniProt Splice Variant | |||||||||||||||||
Entrez Gene | 18440 | ||||||||||||||||
UniGene | Mm.483836 Mm.8032 | ||||||||||||||||
RefSeq | NM_001159561 NM_011028 | ||||||||||||||||
OMIM | |||||||||||||||||
CCDS | CCDS28007 CCDS49778 | ||||||||||||||||
HPRD | |||||||||||||||||
IMGT | |||||||||||||||||
MGI ID | MGI:1337113 | ||||||||||||||||
MGI Symbol | P2rx6 | ||||||||||||||||
EMBL | AC115733 | ||||||||||||||||
GenPept | |||||||||||||||||
RNA Seq Atlas | 18440 | ||||||||||||||||