Mus musculus Gene: Pcdhb16
Summary
InnateDB Gene IDBG-139986.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pcdhb16
Gene Name protocadherin beta 16
Synonyms Pcdhb8; PcdhbP
Species Mus musculus
Ensembl Gene ENSMUSG00000047910
Encoded Proteins
protocadherin beta 16
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000120322:
This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:37477768-37483035
Strand Forward strand
Band B3
Transcripts
ENSMUST00000051442 ENSMUSP00000056347
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
Biological Process
GO:0007156 homophilic cell adhesion
GO:0007268 synaptic transmission
GO:0007416 synapse assembly
GO:0016339 calcium-dependent cell-cell adhesion
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Gene ID
Gene Order
Cross-References
SwissProt
TrEMBL Q8CBD2 Q91Y03 Q925C7 Q925L5
UniProt Splice Variant
Entrez Gene 93887
UniGene Mm.197441
RefSeq NM_053141
OMIM
CCDS CCDS29182
HPRD
IMGT
MGI ID MGI:2136752
MGI Symbol Pcdhb16
EMBL AC020967 AF326309 AF373839 AK036267 AY013777 BC116625 CH466528
GenPept AAI16626 AAK26066 AAK53234 AAK53441 BAC29367 EDL10155
RNA Seq Atlas 93887