Version 5.4
Mus musculus Gene: Taf7
Summary
InnateDB Gene IDBG-140092.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Taf7
Gene Name TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor
Synonyms 55kDa; AI607308; BB007175; Taf2f; TAFII55
Species Mus musculus
Ensembl Gene ENSMUSG00000051316
Encoded Proteins
IDBP-140094
TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000178913:
The intronless gene for this transcription coactivator is located between the protocadherin beta and gamma gene clusters on chromosome 5. The protein encoded by this gene is a component of the TFIID protein complex, a complex which binds to the TATA box in class II promoters and recruits RNA polymerase II and other factors. This particular subunit interacts with the largest TFIID subunit, as well as multiple transcription activators. The protein is required for transcription by promoters targeted by RNA polymerase II. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:37640902-37644204
Strand Reverse strand
Band B3
Transcripts
ENSMUST00000066272 ENSMUSP00000065645
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 36 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 36 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0003713 transcription coactivator activity
GO:0005515 protein binding
GO:0008134 transcription factor binding
GO:0035035 histone acetyltransferase binding
GO:0042809 vitamin D receptor binding
GO:0044212 transcription regulatory region DNA binding
GO:0046966 thyroid hormone receptor binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0006352 DNA-templated transcription, initiation
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0006366 transcription from RNA polymerase II promoter
GO:0006367 transcription initiation from RNA polymerase II promoter
GO:0006469 negative regulation of protein kinase activity
GO:0030520 intracellular estrogen receptor signaling pathway
GO:0035067 negative regulation of histone acetylation
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
Cellular Component
GO:0005634 nucleus
GO:0005669 transcription factor TFIID complex
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0008024 positive transcription elongation factor complex b
GO:0033276 transcription factor TFTC complex
GO:0071339 MLL1 complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000178913
View Gene Order
ENSBTAG00000011945
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu03022
Basal transcription factors pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa03022
Basal transcription factors pathway
INOH
PID NCI
Cross-References
SwissProt Q9R1C0
TrEMBL Q8C291
UniProt Splice Variant
Entrez Gene 24074
UniGene Mm.236009 Mm.398373
RefSeq NM_175770
OMIM
CCDS CCDS29189
HPRD
IMGT
MGI ID MGI:1346348
MGI Symbol Taf7
EMBL AF144562 AK029380 AK076362 AK089054 BC029673
GenPept AAD46767 AAH29673 BAC26429 BAC36313 BAC40723
RNA Seq Atlas 24074

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca