Version 5.4
Mus musculus Gene: Arhgap18
Summary
InnateDB Gene IDBG-140613.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Arhgap18
Gene Name Rho GTPase activating protein 18
Synonyms 4833419J07Rik; AI314906; AI843501
Species Mus musculus
Ensembl Gene ENSMUSG00000039031
Encoded Proteins
IDBP-140615
Rho GTPase activating protein 18
IDBP-711844
IDBP-712042
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000146376:
ARHGAP18 belongs to a family of Rho (see MIM 165390) GTPase-activating proteins that modulate cell signaling (Potkin et al., 2009 [PubMed 19065146]).[supplied by OMIM, Apr 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:26753421-26918648
Strand Forward strand
Band A4
Transcripts
ENSMUST00000039557 ENSMUSP00000044834
ENSMUST00000135866 ENSMUSP00000135783
ENSMUST00000142284
ENSMUST00000176060 ENSMUSP00000135030
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005096 GTPase activator activity
Biological Process
GO:0007165 signal transduction
GO:0043547 positive regulation of GTPase activity
Cellular Component
GO:0005622 intracellular
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000146376
View Gene Order
ENSBTAG00000015381
Not yet available
Pathways
NETPATH
REACTOME
REACT_206918
Signaling by Rho GTPases pathway
REACT_210090
Rho GTPase cycle pathway
REACT_188257
Signal Transduction pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_11051
Rho GTPase cycle pathway
REACT_11044
Signaling by Rho GTPases pathway
REACT_111102
Signal Transduction pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL H3BJL1 H3BLG9
UniProt Splice Variant
Entrez Gene 73910
UniGene Mm.356496
RefSeq NM_176837
OMIM
CCDS CCDS23757
HPRD
IMGT
MGI ID MGI:1921160
MGI Symbol Arhgap18
EMBL AC101709 AC158631
GenPept
RNA Seq Atlas 73910

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca