Version 5.4
Mus musculus Gene: Trpv6
Summary
InnateDB Gene IDBG-140883.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Trpv6
Gene Name transient receptor potential cation channel, subfamily V, member 6
Synonyms Cac; CAT; CaT1; Ecac2; Otrpc3
Species Mus musculus
Ensembl Gene ENSMUSG00000029868
Encoded Proteins
IDBP-140885
transient receptor potential cation channel, subfamily V, member 6
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000165125:
This gene encodes a member of the vanilloid family of transient receptor potential (TRP) calcium channel proteins. Proteins in this TRP family have an N-terminal ankyrin repeat domain, which is required for channel assembly and regulation. [provided by RefSeq, Nov 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:41620621-41636405
Strand Reverse strand
Band B2.1
Transcripts
ENSMUST00000031902 ENSMUSP00000031902
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005216 ion channel activity
GO:0005262 calcium channel activity
GO:0005515 protein binding
GO:0005516 calmodulin binding
Biological Process
GO:0006811 ion transport
GO:0006816 calcium ion transport
GO:0055085 transmembrane transport
GO:0070588 calcium ion transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000165125
View Gene Order
ENSBTAG00000024219
Not yet available
Pathways
NETPATH
REACTOME
REACT_196640
Stimuli-sensing channels pathway
REACT_262350
Ion channel transport pathway
REACT_253400
Transmembrane transport of small molecules pathway
REACT_227861
TRP channels pathway
KEGG
mmu04970
Salivary secretion pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_160189
Stimuli-sensing channels pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_25300
Ion channel transport pathway
REACT_169333
TRP channels pathway
KEGG
hsa04970
Salivary secretion pathway
INOH
PID NCI
cd8tcrpathway
TCR signaling in naïve CD8+ T cells
tcr_pathway
TCR signaling in naïve CD4+ T cells
ptp1bpathway
Signaling events mediated by PTP1B
Cross-References
SwissProt Q91WD2
TrEMBL A2JY27
UniProt Splice Variant
Entrez Gene 64177
UniGene Mm.296889
RefSeq NM_022413
OMIM
CCDS CCDS20052
HPRD
IMGT
MGI ID MGI:1927259
MGI Symbol Trpv6
EMBL AF336378 AJ542487 AK077234 BC016101 CH466533
GenPept AAH16101 AAM53409 BAC36699 CAD62684 EDL13505
RNA Seq Atlas 64177

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca