Version 5.4
Mus musculus Gene: Tnfrsf12a
Summary
InnateDB Gene IDBG-143687.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tnfrsf12a
Gene Name tumor necrosis factor receptor superfamily, member 12a
Synonyms AI255180; C87282; Fn14; HPIP; TWEAK-R; TweakR
Species Mus musculus
Ensembl Gene ENSMUSG00000023905
Encoded Proteins
IDBP-143689
tumor necrosis factor receptor superfamily, member 12a
IDBP-620920
tumor necrosis factor receptor superfamily, member 12a
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 17:23675447-23677449
Strand Reverse strand
Band A3.3
Transcripts
ENSMUST00000024698 ENSMUSP00000024698
ENSMUST00000167059 ENSMUSP00000131574
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0001525 angiogenesis
GO:0006931 substrate-dependent cell migration, cell attachment to substrate
GO:0007155 cell adhesion
GO:0043065 positive regulation of apoptotic process
GO:0045765 regulation of angiogenesis
GO:0045773 positive regulation of axon extension
GO:0061041 regulation of wound healing
GO:0097191 extrinsic apoptotic signaling pathway
GO:2001238 positive regulation of extrinsic apoptotic signaling pathway
Cellular Component
GO:0001726 ruffle
GO:0005886 plasma membrane
GO:0009986 cell surface
GO:0016021 integral component of membrane
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
KEGG
mmu04060
Cytokine-cytokine receptor interaction pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL E9PZT5
UniProt Splice Variant
Entrez Gene 27279
UniGene
RefSeq NM_001161746 NM_013749
OMIM
CCDS CCDS50011 CCDS28456
HPRD
IMGT
MGI ID MGI:1351484
MGI Symbol Tnfrsf12a
EMBL AC154766
GenPept
RNA Seq Atlas 27279

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca