Version 5.4
Mus musculus Gene: Dnaaf2
Summary
InnateDB Gene IDBG-143902.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Dnaaf2
Gene Name dynein, axonemal assembly factor 2
Synonyms 1110034A24Rik; 2810020C19Rik; AV032410; kintoun; Ktu; mknt; TU54
Species Mus musculus
Ensembl Gene ENSMUSG00000020973
Encoded Proteins
IDBP-143904
RIKEN cDNA 1110034A24 gene
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000165506:
This gene encodes a highly conserved protein involved in the preassembly of dynein arm complexes which power cilia. These complexes are found in some cilia and are assembled in the cytoplasm prior to transport for cilia formation. Mutations in this gene have been associated with primary ciliary dyskinesia. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:69189087-69198429
Strand Reverse strand
Band C2
Transcripts
ENSMUST00000021356 ENSMUSP00000021356
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0010033 response to organic substance
GO:0032526 response to retinoic acid
GO:0060285 cilium-dependent cell motility
GO:0070286 axonemal dynein complex assembly
GO:0071973 bacterial-type flagellum-dependent cell motility
Cellular Component
GO:0005737 cytoplasm
GO:0036064 ciliary basal body
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000165506
View Gene Order
ENSBTAG00000004930
Not yet available
Cross-References
SwissProt Q8BPI1
TrEMBL
UniProt Splice Variant
Entrez Gene 109065
UniGene Mm.107180 Mm.467770
RefSeq NM_027269
OMIM
CCDS CCDS25948
HPRD
IMGT
MGI ID MGI:1923566
MGI Symbol Dnaaf2
EMBL AB455811 AK012767 AK075648 AK154254 AK172494 BC055807 BC058344 BC062898
GenPept AAH55807 AAH58344 AAH62898 BAB28455 BAC35879 BAE32466 BAE43032 BAG75151
RNA Seq Atlas 109065

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca