Version 5.4
| Mus musculus Gene: Slc25a14 | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-144059.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Slc25a14 | ||||||||
| Gene Name | solute carrier family 25 (mitochondrial carrier, brain), member 14 | ||||||||
| Synonyms | BMCP1; UCP5; UCP5L; UCP5S | ||||||||
| Species | Mus musculus | ||||||||
| Ensembl Gene | ENSMUSG00000031105 | ||||||||
| Encoded Proteins |
solute carrier family 25 (mitochondrial carrier, brain), member 14
solute carrier family 25 (mitochondrial carrier, brain), member 14
solute carrier family 25 (mitochondrial carrier, brain), member 14
solute carrier family 25 (mitochondrial carrier, brain), member 14
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| Protein Structure | |||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000102078:
Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. This gene is widely expressed in many tissues with the greatest abundance in brain and testis. The gene product has an N-terminal hydrophobic domain that is not present in other UCPs. Two splice variants have been found for this gene. [provided by RefSeq, Jul 2008] Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). Uncoupling proteins separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. Uncoupling proteins facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. This gene is widely expressed in many tissues with the greatest abundance in brain and testis. Alternative splicing results in multiple transcript variants. A pseudogene of this gene has been defined on chromosome 4. [provided by RefSeq, Aug 2013] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome X:48623413-48662294 | ||||||||
| Strand | Forward strand | ||||||||
| Band | A5 | ||||||||
| Transcripts | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Cross-References | |||||||||
| SwissProt | |||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 20523 | ||||||||
| UniGene | Mm.34953 Mm.408071 | ||||||||
| RefSeq | NM_001290703 NM_001290704 XM_006541449 XM_006541450 XM_006541451 XM_006541452 NM_001166450 NM_011398 XM_006541448 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS72376 CCDS30112 CCDS53066 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| MGI ID | MGI:1330823 | ||||||||
| MGI Symbol | Slc25a14 | ||||||||
| EMBL | |||||||||
| GenPept | |||||||||
| RNA Seq Atlas | 20523 | ||||||||