Version 5.4
Mus musculus Gene: Tmem216
Summary
InnateDB Gene IDBG-144298.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tmem216
Gene Name transmembrane protein 216
Synonyms 1110017C22Rik; 2810441K11Rik; 4921533J23Rik; A930021F15Rik; AI482550
Species Mus musculus
Ensembl Gene ENSMUSG00000024667
Encoded Proteins
IDBP-144300
transmembrane protein 216
IDBP-144302
transmembrane protein 216
IDBP-540602
transmembrane protein 216
IDBP-533465
transmembrane protein 216
IDBP-541969
transmembrane protein 216
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a transmembrane protein which is involved in regulation of signaling and trafficking of associated proteins. In humans, mutations in this gene are associated with ciliopathies including Joubert, Meckel and related syndromes. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:10533865-10556238
Strand Reverse strand
Band A
Transcripts
ENSMUST00000059582 ENSMUSP00000059878
ENSMUST00000025569 ENSMUSP00000025569
ENSMUST00000145210 ENSMUSP00000123397
ENSMUST00000123788 ENSMUSP00000119596
ENSMUST00000154383 ENSMUSP00000115319
ENSMUST00000131205
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0042384 cilium assembly
GO:0060271 cilium morphogenesis
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005929 cilium
GO:0016021 integral component of membrane
GO:0035869 ciliary transition zone
GO:0036038 TCTN-B9D complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000187049
View Gene Order
ENSBTAG00000021517
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_001277860 NM_001277861 NM_026798 XM_006527319
OMIM
CCDS CCDS37913 CCDS70934
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca