Homo sapiens Gene: SCARA3
Summary
InnateDB Gene IDBG-14451.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SCARA3
Gene Name scavenger receptor class A, member 3
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000168077
Encoded Proteins
scavenger receptor class A, member 3
scavenger receptor class A, member 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a macrophage scavenger receptor-like protein. This protein has been shown to deplete reactive oxygen species, and thus play an important role in protecting cells from oxidative stress. The expression of this gene is induced by oxidative stress. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:27633868-27676776
Strand Forward strand
Band p21.1
Transcripts
ENST00000337221 ENSP00000337985
ENST00000301904 ENSP00000301904
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005044 scavenger receptor activity
Biological Process
GO:0006898 receptor-mediated endocytosis
GO:0006979 response to oxidative stress
GO:0009650 UV protection
Cellular Component
GO:0000139 Golgi membrane
GO:0005581 collagen trimer
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Cross-References
SwissProt Q6AZY7
TrEMBL
UniProt Splice Variant
Entrez Gene 51435
UniGene Hs.128856
RefSeq NM_016240 NM_182826 XM_005273527
HUGO HGNC:19000
OMIM 602728
CCDS CCDS34870 CCDS34871
HPRD
IMGT
EMBL AB007829 AB007830 BC060811 BC075067 BC075068 DQ205185
GenPept AAH60811 AAH75067 AAH75068 ABA27098 BAA86201 BAA86202
RNA Seq Atlas 51435