Version 5.4
| Mus musculus Gene: Mcc | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-144588.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Mcc | ||||||||
| Gene Name | mutated in colorectal cancers | ||||||||
| Synonyms | |||||||||
| Species | Mus musculus | ||||||||
| Ensembl Gene | ENSMUSG00000071856 | ||||||||
| Encoded Proteins |
mutated in colorectal cancers
mutated in colorectal cancers
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| Protein Structure | |||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000171444:
This gene is a candidate colorectal tumor suppressor gene that is thought to negatively regulate cell cycle progression. The orthologous gene in the mouse expresses a phosphoprotein associated with the plasma membrane and membrane organelles, and overexpression of the mouse protein inhibits entry into S phase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 18:44425061-44812182 | ||||||||
| Strand | Reverse strand | ||||||||
| Band | B3 | ||||||||
| Transcripts |
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| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 221 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathway Predictions based on Human Orthology Data | |||||||||
| NETPATH |
TNFalpha pathway
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| REACTOME | |||||||||
| KEGG | |||||||||
| INOH | |||||||||
| PID NCI | |||||||||
| Cross-References | |||||||||
| SwissProt | |||||||||
| TrEMBL | E9PWI3 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 328949 | ||||||||
| UniGene | Mm.312511 Mm.401023 | ||||||||
| RefSeq | NM_001085373 XM_006526022 XM_006526023 NM_001085374 XM_006526024 XM_006526025 XM_006526026 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS50277 CCDS50276 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| MGI ID | MGI:96930 | ||||||||
| MGI Symbol | Mcc | ||||||||
| EMBL | AC124191 AC137150 AC147551 | ||||||||
| GenPept | |||||||||
| RNA Seq Atlas | 328949 | ||||||||