Mus musculus Gene: Pla2g4c
Summary
InnateDB Gene IDBG-144712.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pla2g4c
Gene Name phospholipase A2, group IVC (cytosolic, calcium-independent)
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000033847
Encoded Proteins
phospholipase A2, group IVC (cytosolic, calcium-independent)
phospholipase A2, group IVC (cytosolic, calcium-independent)
phospholipase A2, group IVC (cytosolic, calcium-independent)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000105499:
This gene encodes a protein which is a member of the phospholipase A2 enzyme family which hydrolyzes glycerophospholipids to produce free fatty acids and lysophospholipids, both of which serve as precursors in the production of signaling molecules. The encoded protein has been shown to be a calcium-independent and membrane bound enzyme. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:13324655-13360672
Strand Forward strand
Band A1
Transcripts
ENSMUST00000043612 ENSMUSP00000043672
ENSMUST00000108528 ENSMUSP00000104168
ENSMUST00000108257
ENSMUST00000167232 ENSMUSP00000127060
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004620 phospholipase activity
GO:0047499 calcium-independent phospholipase A2 activity
Biological Process
GO:0008152 metabolic process
GO:0009395 phospholipid catabolic process
GO:0046475 glycerophospholipid catabolic process
Cellular Component
GO:0005635 nuclear envelope
GO:0005654 nucleoplasm
GO:0005938 cell cortex
Orthologs
Species
Homo sapiens
Gene ID
Gene Order
Pathways
NETPATH
REACTOME
KEGG
Glycerophospholipid metabolism pathway
VEGF signaling pathway pathway
Arachidonic acid metabolism pathway
Ether lipid metabolism pathway
Fc epsilon RI signaling pathway pathway
GnRH signaling pathway pathway
Linoleic acid metabolism pathway
MAPK signaling pathway pathway
alpha-Linolenic acid metabolism pathway
Long-term depression pathway
Vascular smooth muscle contraction pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Hydrolysis of LPE pathway
Acyl chain remodelling of PC pathway
Acyl chain remodelling of PI pathway
Hydrolysis of LPC pathway
Acyl chain remodelling of PE pathway
Metabolism of lipids and lipoproteins pathway
Glycerophospholipid biosynthesis pathway
Phospholipid metabolism pathway
Metabolism pathway
KEGG
alpha-Linolenic acid metabolism pathway
GnRH signaling pathway pathway
Arachidonic acid metabolism pathway
VEGF signaling pathway pathway
Fc epsilon RI signaling pathway pathway
MAPK signaling pathway pathway
Glycerophospholipid metabolism pathway
Linoleic acid metabolism pathway
Long-term depression pathway
Ether lipid metabolism pathway
Vascular smooth muscle contraction pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.223639 Mm.490844
RefSeq NM_001004762 NM_001168504 XM_006539805 XM_006539806 XM_006539807
OMIM
CCDS CCDS39771 CCDS52027
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas