Version 5.4
Mus musculus Gene: Zp1
Summary
InnateDB Gene IDBG-145531.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Zp1
Gene Name zona pellucida glycoprotein 1
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000024734
Encoded Proteins
IDBP-145533
zona pellucida glycoprotein 1
IDBP-619938
zona pellucida glycoprotein 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000149506:
The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. The protein encoded by this gene ensures the structural integrity of the zona pellucida. Mutations in this gene are a cause of oocyte maturation defect and infertility. [provided by RefSeq, May 2014]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:10914287-10920632
Strand Reverse strand
Band A
Transcripts
ENSMUST00000025641 ENSMUSP00000025641
ENSMUST00000168708 ENSMUSP00000128543
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0007338 single fertilization
Cellular Component
GO:0005578 proteinaceous extracellular matrix
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
GO:0030141 secretory granule
GO:0031012 extracellular matrix
Orthologs
Species
Homo sapiens
Gene ID
Gene Order
ENSG00000149506
View Gene Order
Pathways
NETPATH
REACTOME
REACT_199082
Fertilization pathway
REACT_199085
Reproduction pathway
REACT_199072
Interaction With The Zona Pellucida pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_163933
Interaction With The Zona Pellucida pathway
REACT_163914
Fertilization pathway
REACT_163848
Reproduction pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q62005
TrEMBL F7CW32 Q059L1
UniProt Splice Variant
Entrez Gene 22786
UniGene Mm.24767
RefSeq NM_009580
OMIM
CCDS CCDS37918
HPRD
IMGT
MGI ID MGI:103073
MGI Symbol Zp1
EMBL AC132402 BC125613 BC125615 CH466534 U20448 U24227 U24228 U24229 U24230
GenPept AAB60507 AAC48480 AAI25614 AAI25616 EDL41394
RNA Seq Atlas 22786

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca