InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Slc22a16

Summary

InnateDB Gene

IDBG-145732.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Slc22a16

Gene Name

solute carrier family 22 (organic cation transporter), member 16

Synonyms

4921504E14Rik; CT2; FLIPT2; OCT6; OKB1

Species

Mus musculus

Ensembl Gene

ENSMUSG00000019834

Encoded Proteins

IDBP-145734

solute carrier family 22 (organic cation transporter), member 16

IDBP-145736

solute carrier family 22 (organic cation transporter), member 16

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000004809:
This gene encodes a member of the organic zwitterion transporter protein family which transports carnitine. The encoded protein has also been shown to transport anticancer drugs like bleomycin (PMID: 20037140) successful treatment has been correlated with the level of activity of this transporter in tumor cells. [provided by RefSeq, Dec 2011]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 10:40570336-40604132

Strand

Forward strand

Band

Transcripts

ENSMUST00000078314	ENSMUSP00000077428
ENSMUST00000019978	ENSMUSP00000019978

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005275	amine transmembrane transporter activity
GO:0015101	organic cation transmembrane transporter activity
GO:0015226	carnitine transmembrane transporter activity
GO:0022857	transmembrane transporter activity

Biological Process

GO:0007275	multicellular organismal development
GO:0007283	spermatogenesis
GO:0007338	single fertilization
GO:0015695	organic cation transport
GO:0015837	amine transport
GO:0015879	carnitine transport
GO:0030154	cell differentiation
GO:0030317	sperm motility
GO:0046717	acid secretion
GO:0055085	transmembrane transport
GO:1902603	carnitine transmembrane transport