Version 5.4
Mus musculus Gene: Tmx1
Summary
InnateDB Gene IDBG-146019.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tmx1
Gene Name thioredoxin-related transmembrane protein 1
Synonyms 2810425A04Rik; AI465319; Txndc1
Species Mus musculus
Ensembl Gene ENSMUSG00000021072
Encoded Proteins
IDBP-146021
thioredoxin-related transmembrane protein 1
IDBP-531946
thioredoxin-related transmembrane protein 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000139921:
TXNDC1 is a thioredoxin (TXN; see MIM 187700)-related protein with disulfide reductase activity (Matsuo et al., 2001 [PubMed 11152479]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:70453095-70468040
Strand Forward strand
Band C2
Transcripts
ENSMUST00000021471 ENSMUSP00000021471
ENSMUST00000162277 ENSMUSP00000123893
ENSMUST00000160865
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003756 protein disulfide isomerase activity
GO:0015036 disulfide oxidoreductase activity
Biological Process
GO:0006457 protein folding
GO:0034976 response to endoplasmic reticulum stress
GO:0045454 cell redox homeostasis
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005730 nucleolus
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000139921
View Gene Order
ENSBTAG00000011225
Not yet available
Cross-References
SwissProt Q8VBT0
TrEMBL
UniProt Splice Variant
Entrez Gene 72736
UniGene Mm.204670 Mm.490350
RefSeq NM_028339
OMIM
CCDS CCDS25958
HPRD
IMGT
MGI ID MGI:1919986
MGI Symbol Tmx1
EMBL AK013150 AK030429 AK050567 AK137059 AK150511 AK153027 AK170468 BC017603 BC021533
GenPept AAH17603 AAH21533 BAB28680 BAC26960 BAC34326 BAE23223 BAE29624 BAE31660 BAE41816
RNA Seq Atlas 72736

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca