Version 5.4
Mus musculus Gene: Lipt1
Summary
InnateDB Gene IDBG-146391.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Lipt1
Gene Name lipoyltransferase 1
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000037216
Encoded Proteins
IDBP-146393
lipoyltransferase 1
IDBP-532801
lipoyltransferase 1
IDBP-535343
lipoyltransferase 1
IDBP-533297
lipoyltransferase 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000144182:
The process of transferring lipoic acid to proteins is a two-step process. The first step is the activation of lipoic acid by lipoate-activating enzyme to form lipoyl-AMP. For the second step, the protein encoded by this gene transfers the lipoyl moiety to apoproteins. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 13. Read-through transcription also exists between this gene and the neighboring downstream mitochondrial ribosomal protein L30 (MRPL30) gene. [provided by RefSeq, Mar 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:37871738-37877387
Strand Forward strand
Band B
Transcripts
ENSMUST00000041621 ENSMUSP00000038739
ENSMUST00000128085 ENSMUSP00000119243
ENSMUST00000142670 ENSMUSP00000122160
ENSMUST00000144440 ENSMUSP00000115465
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016740 transferase activity
GO:0016746 transferase activity, transferring acyl groups
Biological Process
GO:0006464 cellular protein modification process
GO:0008150 biological_process
GO:0009249 protein lipoylation
Cellular Component
GO:0005739 mitochondrion
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000144182
View Gene Order
ENSBTAG00000003965
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu00785
Lipoic acid metabolism pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa00785
Lipoic acid metabolism pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.389100
RefSeq NM_001037918 XM_006496174 XM_006496175 XM_006496176 XM_006496177 XM_006496178
OMIM
CCDS CCDS14895
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca