Version 5.4
Mus musculus Gene: Mpp6
Summary
InnateDB Gene IDBG-146671.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mpp6
Gene Name membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
Synonyms P55t; Pals2
Species Mus musculus
Ensembl Gene ENSMUSG00000038388
Encoded Proteins
IDBP-146673
membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
IDBP-146675
membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
IDBP-627542
membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
IDBP-627543
membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
IDBP-627544
membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000105926:
Members of the peripheral membrane-associated guanylate kinase (MAGUK) family function in tumor suppression and receptor clustering by forming multiprotein complexes containing distinct sets of transmembrane, cytoskeletal, and cytoplasmic signaling proteins. All MAGUKs contain a PDZ-SH3-GUK core and are divided into 4 subfamilies, DLG-like (see DLG1; MIM 601014), ZO1-like (see TJP1; MIM 601009), p55-like (see MPP1; MIM 305360), and LIN2-like (see CASK; MIM 300172), based on their size and the presence of additional domains. MPP6 is a member of the p55-like MAGUK subfamily (Tseng et al., 2001 [PubMed 11311936]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:50110241-50198598
Strand Forward strand
Band B2.3
Transcripts
ENSMUST00000036225 ENSMUSP00000038772
ENSMUST00000036236 ENSMUSP00000039314
ENSMUST00000166318 ENSMUSP00000125880
ENSMUST00000171601 ENSMUSP00000129004
ENSMUST00000167628 ENSMUSP00000129355
ENSMUST00000167063
ENSMUST00000167319
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 18 interaction(s) predicted by orthology.
Experimentally validated
Total 7 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 18 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004385 guanylate kinase activity
GO:0005515 protein binding
GO:0030165 PDZ domain binding
Biological Process
GO:0046939 nucleotide phosphorylation
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000105926
View Gene Order
ENSBTAG00000015303
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_001164733 NM_001164734 NM_019939
OMIM
CCDS CCDS20128 CCDS51770
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca