Version 5.4
Homo sapiens Gene: LPAR5
Summary
InnateDB Gene IDBG-14669.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LPAR5
Gene Name lysophosphatidic acid receptor 5
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000184574
Encoded Proteins
IDBP-14671
lysophosphatidic acid receptor 5
IDBP-364036
lysophosphatidic acid receptor 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the rhodopsin class of G protein-coupled transmembrane receptors. This protein transmits extracellular signals from lysophosphatidic acid to cells through heterotrimeric G proteins and mediates numerous cellular processes. Many G protein receptors serve as targets for pharmaceutical drugs. Transcript variants of this gene have been described.[provided by RefSeq, Dec 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:6618835-6636447
Strand Reverse strand
Band p13.31
Transcripts
ENST00000329858 ENSP00000327875
ENST00000431922 ENSP00000393098
ENST00000540335
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0004930 G-protein coupled receptor activity
Biological Process
GO:0007186 G-protein coupled receptor signaling pathway
GO:0008150 biological_process
Cellular Component
GO:0005575 cellular_component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000067714
View Gene Order
ENSBTAG00000004541
Not yet available
Pathways
NETPATH
REACTOME
REACT_18283
G alpha (q) signalling events pathway
REACT_120966
Gastrin-CREB signalling pathway via PKC and MAPK pathway
REACT_19231
G alpha (i) signalling events pathway
REACT_18365
Lysosphingolipid and LPA receptors pathway
REACT_14828
Class A/1 (Rhodopsin-like receptors) pathway
REACT_14797
Signaling by GPCR pathway
REACT_111102
Signal Transduction pathway
REACT_19184
GPCR downstream signaling pathway
REACT_21340
GPCR ligand binding pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q9H1C0
TrEMBL Q5KU18
UniProt Splice Variant
Entrez Gene 57121
UniGene Hs.155538
RefSeq NM_001142961 NM_020400
HUGO HGNC:13307
OMIM 606926
CCDS CCDS8553
HPRD 09495
IMGT
EMBL AB041943 AB083600 AF411112 AJ272207 AK313127 BC033571 BC072394 CH471116 HQ995529
GenPept AAH33571 AAH72394 AAL26483 ADZ31974 BAB89313 BAD83597 BAG35947 CAC03715 EAW88775 EAW88776
RNA Seq Atlas 57121

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca