InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Mrpl50

Summary

InnateDB Gene

IDBG-146990.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Mrpl50

Gene Name

mitochondrial ribosomal protein L50

Synonyms

AA408971; AI317351; D4Wsu125e

Species

Mus musculus

Ensembl Gene

ENSMUSG00000044018

Encoded Proteins

IDBP-146992

mitochondrial ribosomal protein L50

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000136897:
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a putative 39S subunit protein and belongs to the L47P ribosomal protein family. Pseudogenes corresponding to this gene are found on chromosomes 2p, 2q, 5p, and 10q. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 4:49512596-49521093

Strand

Reverse strand

Band

Transcripts

ENSMUST00000057829

ENSMUSP00000062476

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 23 interaction(s) predicted by orthology.