Version 5.4
Mus musculus Gene: Kcnt1
Summary
InnateDB Gene IDBG-147335.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Kcnt1
Gene Name potassium channel, subfamily T, member 1
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000058740
Encoded Proteins
IDBP-147337
potassium channel, subfamily T, member 1
IDBP-252308
potassium channel, subfamily T, member 1
IDBP-252310
potassium channel, subfamily T, member 1
IDBP-252312
potassium channel, subfamily T, member 1
IDBP-626397
potassium channel, subfamily T, member 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000107147:
Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a sodium-activated potassium channel subunit which is thought to function in ion conductance and developmental signaling pathways. Mutations in this gene cause the early-onset epileptic disorders, malignant migrating partial seizures of infancy and autosomal dominant nocturnal frontal lobe epilepsy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:25863795-25918273
Strand Forward strand
Band A3
Transcripts
ENSMUST00000037580 ENSMUSP00000039058
ENSMUST00000114176 ENSMUSP00000109813
ENSMUST00000114172 ENSMUSP00000109809
ENSMUST00000114170 ENSMUSP00000109807
ENSMUST00000150788
ENSMUST00000131529
ENSMUST00000138568
ENSMUST00000128502
ENSMUST00000153001
ENSMUST00000145544
ENSMUST00000171268 ENSMUSP00000132212
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005249 voltage-gated potassium channel activity
GO:0015269 calcium-activated potassium channel activity
Biological Process
GO:0006813 potassium ion transport
GO:0071805 potassium ion transmembrane transport
Cellular Component
GO:0008076 voltage-gated potassium channel complex
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000107147
View Gene Order
ENSBTAG00000018975
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.401525
RefSeq NM_001145403 NM_175462 XM_006497880 XM_006497881 XM_006497885 XM_006497887 XM_006497892
OMIM
CCDS CCDS15794 CCDS50537
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca