InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Srpr

Summary

InnateDB Gene

IDBG-148260.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Srpr

Gene Name

signal recognition particle receptor ('docking protein')

Synonyms

1300011P19Rik; D11Mgi27

Species

Mus musculus

Ensembl Gene

ENSMUSG00000032042

Encoded Proteins

IDBP-148262

signal recognition particle receptor ('docking protein')

IDBP-534393

signal recognition particle receptor ('docking protein')

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000182934:
The gene encodes a subunit of the endoplasmic reticulum signal recognition particle receptor that, in conjunction with the signal recognition particle, is involved in the targeting and translocation of signal sequence tagged secretory and membrane proteins across the endoplasmic reticulum. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2010]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 9:35200175-35247973

Strand

Forward strand

Band

Transcripts

ENSMUST00000034541	ENSMUSP00000034541
ENSMUST00000138287
ENSMUST00000154005
ENSMUST00000132799	ENSMUSP00000115104

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	1 [view]
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	7 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0003924	GTPase activity
GO:0005047	signal recognition particle binding
GO:0005525	GTP binding
GO:0017111	nucleoside-triphosphatase activity
GO:0044822	poly(A) RNA binding

Biological Process

GO:0006184	GTP catabolic process
GO:0006614	SRP-dependent cotranslational protein targeting to membrane
GO:0006810	transport
GO:0006886	intracellular protein transport