Version 5.4
Homo sapiens Gene: UQCR11
Summary
InnateDB Gene IDBG-14843.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol UQCR11
Gene Name ubiquinol-cytochrome c reductase, complex III subunit XI
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000127540
Encoded Proteins
IDBP-762793
IDBP-761882
IDBP-765204
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes the smallest known component of the ubiquinol-cytochrome c reductase complex, which forms part of the mitochondrial respiratory chain. The encoded protein may function as a binding factor for the iron-sulfur protein in this complex. [provided by RefSeq, Oct 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:1597172-1605490
Strand Reverse strand
Band p13.3
Transcripts
ENST00000591899 ENSP00000467262
ENST00000593264
ENST00000593029
ENST00000585671 ENSP00000466420
ENST00000589880 ENSP00000467555
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008121 ubiquinol-cytochrome-c reductase activity
GO:0009055 electron carrier activity
Biological Process
GO:0006091 generation of precursor metabolites and energy
GO:0022904 respiratory electron transport chain
GO:0044237 cellular metabolic process
GO:0044281 small molecule metabolic process
GO:1902600 hydrogen ion transmembrane transport
Cellular Component
GO:0005743 mitochondrial inner membrane
GO:0016021 integral component of membrane
GO:0070469 respiratory chain
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
REACT_22393
Respiratory electron transport pathway
REACT_6305
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. pathway
REACT_111083
The citric acid (TCA) cycle and respiratory electron transport pathway
REACT_111217
Metabolism pathway
KEGG
hsa05010
Alzheimer's disease pathway
hsa00190
Oxidative phosphorylation pathway
hsa05012
Parkinson's disease pathway
hsa05016
Huntington's disease pathway
hsa04260
Cardiac muscle contraction pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_006830
HUGO
OMIM
CCDS CCDS12073
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca