Version 5.4
Mus musculus Gene: Ift172
Summary
InnateDB Gene IDBG-148718.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ift172
Gene Name intraflagellar transport 172
Synonyms 4930553F24Rik; avc1; Slb; wim
Species Mus musculus
Ensembl Gene ENSMUSG00000038564
Encoded Proteins
IDBP-148720
intraflagellar transport 172 homolog (Chlamydomonas)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000138002:
Gene Information
Type Protein coding
Genomic Location Chromosome 5:31253280-31291114
Strand Reverse strand
Band B1
Transcripts
ENSMUST00000041565 ENSMUSP00000049335
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0001841 neural tube formation
GO:0001843 neural tube closure
GO:0001947 heart looping
GO:0007219 Notch signaling pathway
GO:0007224 smoothened signaling pathway
GO:0007368 determination of left/right symmetry
GO:0007420 brain development
GO:0007507 heart development
GO:0008544 epidermis development
GO:0008589 regulation of smoothened signaling pathway
GO:0009953 dorsal/ventral pattern formation
GO:0016485 protein processing
GO:0021522 spinal cord motor neuron differentiation
GO:0021915 neural tube development
GO:0031122 cytoplasmic microtubule organization
GO:0042384 cilium assembly
GO:0045880 positive regulation of smoothened signaling pathway
GO:0050680 negative regulation of epithelial cell proliferation
GO:0060021 palate development
GO:0060173 limb development
GO:0060271 cilium morphogenesis
GO:0060348 bone development
GO:0061525 hindgut development
GO:0070986 left/right axis specification
Cellular Component
GO:0005929 cilium
GO:0030992 intraciliary transport particle B
GO:0031514 motile cilium
GO:0036064 ciliary basal body
GO:0097225 sperm midpiece
GO:0097228 sperm principal piece
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000138002
View Gene Order
ENSBTAG00000018157
Not yet available
Pathways
NETPATH
REACTOME
REACT_269412
Hedgehog 'off' state pathway
REACT_250064
Signaling by Hedgehog pathway
REACT_188257
Signal Transduction pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_228134
Signaling by Hedgehog pathway
REACT_111102
Signal Transduction pathway
REACT_267634
Hedgehog 'off' state pathway
KEGG
INOH
PID NCI
hedgehog_glipathway
Hedgehog signaling events mediated by Gli proteins
Cross-References
SwissProt Q6VH22
TrEMBL
UniProt Splice Variant
Entrez Gene 67661
UniGene
RefSeq NM_026298
OMIM
CCDS CCDS39054
HPRD
IMGT
MGI ID MGI:2682064
MGI Symbol Ift172
EMBL AK006007 AK122461 AY339616 BC051928 BC060948 BC066096
GenPept AAH51928 AAH60948 AAH66096 AAR05390 BAB24362 BAC65743
RNA Seq Atlas 67661

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca