Homo sapiens Gene: KCNK10 | |||||||||||||||||||
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Summary | |||||||||||||||||||
InnateDB Gene | IDBG-14892.6 | ||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||
Gene Symbol | KCNK10 | ||||||||||||||||||
Gene Name | potassium channel, subfamily K, member 10 | ||||||||||||||||||
Synonyms | |||||||||||||||||||
Species | Homo sapiens | ||||||||||||||||||
Ensembl Gene | ENSG00000100433 | ||||||||||||||||||
Encoded Proteins |
potassium channel, subfamily K, member 10
potassium channel, subfamily K, member 10
potassium channel, subfamily K, member 10
potassium channel, subfamily K, member 10
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Protein Structure | |||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||
Entrez Gene | |||||||||||||||||||
Summary |
The protein encoded by this gene belongs to the family of potassium channel proteins containing two pore-forming P domains. This channel is an open rectifier which primarily passes outward current under physiological K+ concentrations, and is stimulated strongly by arachidonic acid and to a lesser degree by membrane stretching, intracellular acidification, and general anaesthetics. Several alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Sep 2008] |
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Gene Information | |||||||||||||||||||
Type | Protein coding | ||||||||||||||||||
Genomic Location | Chromosome 14:88180103-88326907 | ||||||||||||||||||
Strand | Reverse strand | ||||||||||||||||||
Band | q31.3 | ||||||||||||||||||
Transcripts |
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Interactions | |||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
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Gene Ontology | |||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||
Species
Mus musculus
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||||||||||||||
NETPATH | |||||||||||||||||||
REACTOME |
TWIK related potassium channel (TREK) pathway
Tandem pore domain potassium channels pathway
Neuronal System pathway
Potassium Channels pathway
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KEGG |
Gastric acid secretion pathway
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INOH | |||||||||||||||||||
PID NCI | |||||||||||||||||||
Cross-References | |||||||||||||||||||
SwissProt | P57789 | ||||||||||||||||||
TrEMBL | |||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||
Entrez Gene | 54207 | ||||||||||||||||||
UniGene | |||||||||||||||||||
RefSeq | NM_138317 NM_021161 NM_138318 | ||||||||||||||||||
HUGO | HGNC:6273 | ||||||||||||||||||
OMIM | 605873 | ||||||||||||||||||
CCDS | CCDS9881 CCDS9880 CCDS9882 | ||||||||||||||||||
HPRD | 12061 | ||||||||||||||||||
IMGT | |||||||||||||||||||
EMBL | AF279890 AF385399 AF385400 AK313499 AK315263 AL049834 AL133279 BC075021 BC075022 CH471061 EU978938 EU978939 EU978940 EU978941 | ||||||||||||||||||
GenPept | AAG15191 AAH75021 AAH75022 AAL95705 AAL95706 ACH86097 ACH86098 ACH86099 ACH86100 BAG36281 BAG37680 EAW81373 EAW81374 EAW81375 | ||||||||||||||||||
RNA Seq Atlas | 54207 | ||||||||||||||||||