Version 5.4
Mus musculus Gene: Mmrn2
Summary
InnateDB Gene IDBG-149603.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mmrn2
Gene Name multimerin 2
Synonyms AA986839; Emilin3; EndoGlyx-1; ENDOGLYX1
Species Mus musculus
Ensembl Gene ENSMUSG00000041445
Encoded Proteins
IDBP-257133
multimerin 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000173269:
This gene encodes a protein belonging to the member of elastin microfibril interface-located (EMILIN) protein family. This family member is an extracellular matrix glycoprotein that can interfere with tumor angiogenesis and growth. It serves as a transforming growth factor beta antagonist and can interfere with the VEGF-A/VEGFR2 pathway. A related pseudogene has been identified on chromosome 6. [provided by RefSeq, Aug 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:34375504-34404287
Strand Forward strand
Band B
Transcripts
ENSMUST00000111908 ENSMUSP00000107539
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0001525 angiogenesis
GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway
GO:0090051 negative regulation of cell migration involved in sprouting angiogenesis
Cellular Component
GO:0005604 basement membrane
GO:0005615 extracellular space
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000173269
View Gene Order
ENSBTAG00000003510
Not yet available
Cross-References
SwissProt A6H6E2
TrEMBL
UniProt Splice Variant
Entrez Gene 105450
UniGene Mm.272673
RefSeq NM_153127
OMIM
CCDS CCDS36876
HPRD
IMGT
MGI ID MGI:2385618
MGI Symbol Mmrn2
EMBL AK078470 BC034871 BC145845 CH466573
GenPept AAH34871 AAI45846 BAC37291 EDL24879
RNA Seq Atlas 105450

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca