Version 5.4
Mus musculus Gene: Rgr
Summary
InnateDB Gene IDBG-150927.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Rgr
Gene Name retinal G protein coupled receptor
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000021804
Encoded Proteins
IDBP-150929
retinal G protein coupled receptor
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The gene is a member of the opsin family of G-protein coupled receptors. The encoded protein is expressed in the retina, and acts as a photoisomerase to catalyze the conversion of all-trans-retinal to 11-cis-retinal. Disruption of a similar gene in human is associated with autosomal recessive (arRP) and autosomal dominant retinitis pigmentosa (adRP). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:37037490-37048964
Strand Reverse strand
Band B
Transcripts
ENSMUST00000022338 ENSMUSP00000022338
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004930 G-protein coupled receptor activity
GO:0004950 chemokine receptor activity
GO:0005515 protein binding
GO:0009881 photoreceptor activity
Biological Process
GO:0006935 chemotaxis
GO:0007186 G-protein coupled receptor signaling pathway
GO:0007601 visual perception
GO:0007602 phototransduction
GO:0018298 protein-chromophore linkage
GO:0070098 chemokine-mediated signaling pathway
Cellular Component
GO:0005887 integral component of plasma membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000148604
View Gene Order
ENSBTAG00000015681
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_19231
G alpha (i) signalling events pathway
REACT_18426
Opsins pathway
REACT_14828
Class A/1 (Rhodopsin-like receptors) pathway
REACT_14797
Signaling by GPCR pathway
REACT_111102
Signal Transduction pathway
REACT_19184
GPCR downstream signaling pathway
REACT_21340
GPCR ligand binding pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_021340
OMIM
CCDS CCDS26949
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca