Version 5.4
Mus musculus Gene: Gpihbp1
Summary
InnateDB Gene IDBG-151003.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gpihbp1
Gene Name GPI-anchored HDL-binding protein 1
Synonyms 1110002J19Rik; GPI-HBP1
Species Mus musculus
Ensembl Gene ENSMUSG00000022579
Encoded Proteins
IDBP-151005
GPI-anchored HDL-binding protein 1
IDBP-787697
GPI-anchored HDL-binding protein 1
IDBP-787699
GPI-anchored HDL-binding protein 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog null:
Dietary fats are packaged by intestine into triglyceride-rich lipoproteins called chylomicrons. The triglycerides in chylomicrons are hydrolyzed by lipoprotein lipase (LPL: MIM 609708) along the luminal surface of capillaries, mainly in heart, skeletal muscle, and adipose tissue. GPIHBP1 is a capillary endothelial cell protein that provides a platform for LPL-mediated processing of chylomicrons (Beigneux et al., 2007 [PubMed 17403372]).[supplied by OMIM, Apr 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:75596628-75599481
Strand Forward strand
Band D3
Transcripts
ENSMUST00000023243 ENSMUSP00000023243
ENSMUST00000189944 ENSMUSP00000139511
ENSMUST00000189874 ENSMUSP00000139792
ENSMUST00000190119
ENSMUST00000186934
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008035 high-density lipoprotein particle binding
GO:0008289 lipid binding
GO:0008320 protein transmembrane transporter activity
GO:0034185 apolipoprotein binding
GO:0035473 lipase binding
GO:0035478 chylomicron binding
GO:0071813 lipoprotein particle binding
Biological Process
GO:0006869 lipid transport
GO:0006886 intracellular protein transport
GO:0017038 protein import
GO:0034394 protein localization to cell surface
GO:0042632 cholesterol homeostasis
GO:0045056 transcytosis
GO:0050821 protein stabilization
GO:0051006 positive regulation of lipoprotein lipase activity
GO:0070328 triglyceride homeostasis
GO:0071503 response to heparin
GO:0071806 protein transmembrane transport
GO:0090319 positive regulation of chylomicron remodeling
GO:0090321 positive regulation of chylomicron remnant clearance
Cellular Component
GO:0009897 external side of plasma membrane
GO:0009986 cell surface
GO:0016323 basolateral plasma membrane
GO:0016324 apical plasma membrane
GO:0031362 anchored component of external side of plasma membrane
GO:0034364 high-density lipoprotein particle
GO:0046658 anchored component of plasma membrane
Orthologs
Species
Homo sapiens
Gene ID
Gene Order
null
View Gene Order
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_026730 XM_006521314 XM_006521315
OMIM
CCDS CCDS27545
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca