Version 5.4
Mus musculus Gene: Olfr145
Summary
InnateDB Gene IDBG-151060.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Olfr145
Gene Name olfactory receptor 145
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000066748
Encoded Proteins
IDBP-151062
olfactory receptor 145
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:37897325-37898375
Strand Forward strand
Band A4
Transcripts
ENSMUST00000086062 ENSMUSP00000083229
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004930 G-protein coupled receptor activity
GO:0004984 olfactory receptor activity
Biological Process
GO:0007186 G-protein coupled receptor signaling pathway
GO:0007608 sensory perception of smell
GO:0050911 detection of chemical stimulus involved in sensory perception of smell
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000197125
View Gene Order
ENSBTAG00000038345
Not yet available
Pathways
NETPATH
REACTOME
REACT_223625
GPCR downstream signaling pathway
REACT_254215
Signaling by GPCR pathway
REACT_252270
Olfactory Signaling Pathway pathway
REACT_188257
Signal Transduction pathway
KEGG
mmu04740
Olfactory transduction pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_15488
Olfactory Signaling Pathway pathway
REACT_14797
Signaling by GPCR pathway
REACT_111102
Signal Transduction pathway
REACT_19184
GPCR downstream signaling pathway
KEGG
hsa04740
Olfactory transduction pathway
INOH
PID NCI
Cross-References
SwissProt Q60882
TrEMBL B2RQ58
UniProt Splice Variant
Entrez Gene 258310
UniGene Mm.377430
RefSeq NM_146313
OMIM
CCDS CCDS22990
HPRD
IMGT
MGI ID MGI:2177528
MGI Symbol Olfr145
EMBL AF282279 AY073780 AY318060 BC137773 CH466522 U28771
GenPept AAC52394 AAG39864 AAI37774 AAL61443 AAP71357 EDL25448
RNA Seq Atlas 258310

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca