InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Gabrq

Summary

InnateDB Gene

IDBG-151314.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Gabrq

Gene Name

gamma-aminobutyric acid (GABA) A receptor, subunit theta

Synonyms

Species

Mus musculus

Ensembl Gene

ENSMUSG00000031344

Encoded Proteins

IDBP-151316

gamma-aminobutyric acid (GABA) A receptor, subunit theta

IDBP-251525

gamma-aminobutyric acid (GABA) A receptor, subunit theta

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog null:
The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes the theta subunit of the GABA A receptor. The gene is mapped to chromosome Xq28 in a cluster of genes including those that encode the alpha 3 and epsilon subunits of the GABA A receptor. This gene location is also the candidate region of two different neurologic diseases: early-onset parkinsonism (Waisman syndrome) and X-linked mental retardation (MRX3). [provided by RefSeq, Nov 2009]

Gene Information

Type

Protein coding

Genomic Location

Chromosome X:72825178-72842602

Strand

Forward strand

Band

A7.3

Transcripts

ENSMUST00000033711	ENSMUSP00000033711
ENSMUST00000114553	ENSMUSP00000110200

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.

Experimentally validated
Total	1 [view]
Protein-Protein	0
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004890	GABA-A receptor activity
GO:0005230	extracellular ligand-gated ion channel activity
GO:0005254	chloride channel activity

Biological Process

GO:0006810	transport
GO:0006811	ion transport
GO:0006821	chloride transport
GO:0007214	gamma-aminobutyric acid signaling pathway
GO:0034220	ion transmembrane transport
GO:1902476	chloride transmembrane transport

Cellular Component

GO:0005887	integral component of plasma membrane
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0030054	cell junction
GO:0034707	chloride channel complex
GO:0043235	receptor complex
GO:0045202	synapse
GO:0045211	postsynaptic membrane