Version 5.4
| Mus musculus Gene: B3galnt1 | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-151548.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | B3galnt1 | ||||||||
| Gene Name | UDP-GalNAc:betaGlcNAc beta 1,3-galactosaminyltransferase, polypeptide 1 | ||||||||
| Synonyms | B3galt3; b3GT3 | ||||||||
| Species | Mus musculus | ||||||||
| Ensembl Gene | ENSMUSG00000043300 | ||||||||
| Encoded Proteins |
UDP-GalNAc:betaGlcNAc beta 1,3-galactosaminyltransferase, polypeptide 1
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000169255:
This gene is a member of the beta-1,3-galactosyltransferase (beta3GalT) gene family. This family encodes type II membrane-bound glycoproteins with diverse enzymatic functions using different donor substrates (UDP-galactose and UDP-N-acetylglucosamine) and different acceptor sugars (N-acetylglucosamine, galactose, N-acetylgalactosamine). The beta3GalT genes are distantly related to the Drosophila Brainiac gene and have the protein coding sequence contained in a single exon. The beta3GalT proteins also contain conserved sequences not found in the beta4GalT or alpha3GalT proteins. The carbohydrate chains synthesized by these enzymes are designated as type 1, whereas beta4GalT enzymes synthesize type 2 carbohydrate chains. The ratio of type 1:type 2 chains changes during embryogenesis. By sequence similarity, the beta3GalT genes fall into at least two groups: beta3GalT4 and 4 other beta3GalT genes (beta3GalT1-3, beta3GalT5). The encoded protein of this gene does not use N-acetylglucosamine as an acceptor sugar at all. Multiple transcript variants that are alternatively spliced in the 5' UTR have been described; they all encode the same protein. [provided by RefSeq, Jul 2008] This gene is a member of the beta-1,3-galactosyltransferase (beta3GalT) gene family. This family encodes type II membrane-bound glycoproteins with diverse enzymatic functions using different donor substrates (UDP-galactose and UDP-N-acetylglucosamine) and different acceptor sugars (N-acetylglucosamine, galactose, N-acetylgalactosamine). The beta3GalT genes are distantly related to the Drosophila Brainiac gene and have the protein coding sequence contained in a single exon. The beta3GalT proteins also contain conserved sequences not found in the beta4GalT or alpha3GalT proteins. The carbohydrate chains synthesized by these enzymes are designated as type 1, whereas beta4GalT enzymes synthesize type 2 carbohydrate chains. The ratio of type 1:type 2 chains changes during embryogenesis. By sequence similarity, the beta3GalT genes fall into at least two groups: beta3GalT4 and 4 other beta3GalT genes (beta3GalT1-3, beta3GalT5). The encoded protein of this gene does not use N-acetylglucosamine as an acceptor sugar at all. Multiple transcript variants that are alternatively spliced in the 5\' UTR have been described; they all encode the same protein. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 3:69574186-69598861 | ||||||||
| Strand | Reverse strand | ||||||||
| Band | E1 | ||||||||
| Transcripts |
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| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||||
| NETPATH | |||||||||
| REACTOME | |||||||||
| KEGG |
Glycosphingolipid biosynthesis pathway
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| INOH | |||||||||
| PID NCI | |||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||
| NETPATH | |||||||||
| REACTOME | |||||||||
| KEGG |
Glycosphingolipid biosynthesis pathway
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| INOH | |||||||||
| PID NCI | |||||||||
| Cross-References | |||||||||
| SwissProt | Q920V1 | ||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 26879 | ||||||||
| UniGene | Mm.153710 Mm.415922 | ||||||||
| RefSeq | NM_020026 XM_006501529 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS17406 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| MGI ID | MGI:1349405 | ||||||||
| MGI Symbol | B3galnt1 | ||||||||
| EMBL | AB039154 AB039155 AB039156 AB039157 AB039158 AB039159 AB039160 AB039161 AB039162 AF029792 AK003837 AK088407 BC003835 | ||||||||
| GenPept | AAC53525 AAH03835 BAB23028 BAB68678 BAB68679 BAB68680 BAB68681 BAB68682 BAB68683 BAB68684 BAB68685 BAB68686 BAC40336 | ||||||||
| RNA Seq Atlas | 26879 | ||||||||