Version 5.4
Homo sapiens Gene: BTBD2
Summary
InnateDB Gene IDBG-15254.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BTBD2
Gene Name BTB (POZ) domain containing 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000133243
Encoded Proteins
IDBP-15256
BTB (POZ) domain containing 2
IDBP-813587
BTB (POZ) domain containing 2
IDBP-813588
BTB (POZ) domain containing 2
IDBP-760001
IDBP-813586
BTB (POZ) domain containing 2
IDBP-764873
IDBP-813581
BTB (POZ) domain containing 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The C-terminus of the protein encoded by this gene binds topoisomerase I. The N-terminus contains a proline-rich region and a BTB/POZ domain (broad-complex, Tramtrack and bric a brac/Pox virus and Zinc finger), both of which are typically involved in protein-protein interactions. Subcellularly, the protein localizes to cytoplasmic bodies. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:1985438-2034881
Strand Reverse strand
Band p13.3
Transcripts
ENST00000255608 ENSP00000255608
ENST00000587742 ENSP00000483892
ENST00000588395 ENSP00000478992
ENST00000589685
ENST00000589200 ENSP00000466686
ENST00000590646 ENSP00000481529
ENST00000587225
ENST00000587825 ENSP00000467113
ENST00000592895
ENST00000592082 ENSP00000481163
ENST00000611545
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 39 experimentally validated interaction(s) in this database.
Experimentally validated
Total 39 [view]
Protein-Protein 39 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
GO:0000932 cytoplasmic mRNA processing body
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000003344
View Gene Order
ENSBTAG00000016108
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.465543 Hs.675714
RefSeq NM_017797 XM_005259593
HUGO
OMIM
CCDS CCDS12078
HPRD 12252
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca