Version 5.4
Mus musculus Gene: Pvr
Summary
InnateDB Gene IDBG-152745.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pvr
Gene Name poliovirus receptor
Synonyms 3830421F03Rik; CD155; D7Ertd458e; HVED; mE4; necl-5; PVS; Taa1; Tage4
Species Mus musculus
Ensembl Gene ENSMUSG00000040511
Encoded Proteins
IDBP-152747
poliovirus receptor
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 7:19903578-19921160
Strand Reverse strand
Band A3
Transcripts
ENSMUST00000043517 ENSMUSP00000039205
ENSMUST00000159413
ENSMUST00000160572
ENSMUST00000159261
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0001618 virus receptor activity
GO:0005515 protein binding
GO:0050839 cell adhesion molecule binding
Biological Process
GO:0002860 positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target
GO:0009615 response to virus
GO:0016337 single organismal cell-cell adhesion
GO:0016477 cell migration
GO:0042271 susceptibility to natural killer cell mediated cytotoxicity
GO:0045954 positive regulation of natural killer cell mediated cytotoxicity
GO:0060370 susceptibility to T cell mediated cytotoxicity
Cellular Component
GO:0005634 nucleus
GO:0005886 plasma membrane
GO:0009986 cell surface
GO:0016021 integral component of membrane
GO:0030054 cell junction
GO:0070062 extracellular vesicular exosome
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
KEGG
mmu04514
Cell adhesion molecules (CAMs) pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.227506 Mm.405398 Mm.446888
RefSeq NM_027514
OMIM
CCDS CCDS20916
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca